中药口服与灌肠联合必需氨基酸治疗慢性肾功能衰竭103例观察

为了探讨慢性肾衰的有效治疗方法,本文采用温补脾肾中药口服、祛邪泄浊中药灌肠及必需氨基酸注射的联合方案治疗慢性肾衰103例。结果血尿素氮(BUN)及血肌酐(Scr)均比治前显著降低(P<0.01),内生肌酐清除率(Ccr)比治前增高(P<0.05)。43例Scr降至正常,总有效率86.4%。其中观察1年以上者60例,27例肾功能保持正常,20例Scr稳定在出院时水平,另13例虽Scr有所上升,但仅3例发展为终末期肾衰。作者认为这一方案不仅对慢性肾衰近期疗效较好,而且有延缓慢性肾衰进展的作用。

Observation on Oral and Rectal Administration of Chinese Herbal and Essential Amino Acids Injection in 103 Cases of Chronic Renal Failure

103 cases of chronic renal failure (CRF), were treated by oral taken drugs for warming andreplenishing Spleen and Kidney, rectal given drugs for expelling and purgating the pathogenic factorand injection of essential amino-acid (EAA). Results: BUN and Scr of patients reduced obviouslythan that of pre-treatment(P<0.05), but Ccr increased (P<0.05), Scr of 43 cases normalizedeventually, the total effective rate was 86.47%. 60 of 103 cases were observed for more than one year,the kidney function of 27 cases remained to be normal, Scr of 20 cases stabilized at the level ofdischarging from hospital. Although the Scr of 13 cases increased slightly, bot 3 cases developed tothe terminal stage of CRF only. It is considered that this program was effective not only forimmediate efficacy, but also could delay the progress of CRF.