针挑治疗原发不育精子异常临床与机理研究

目的：寻找提高治疗原发精子异常临床疗效的最佳方法。方法：将168例患者随机分为两组，治疗组85例针挑生殖点、骶丛神经点、腰2神经点为主；对照组83例口服五子衍宗丸。在3家医院进行了多中心疗效观察。结果：治疗组总有效率为83．5％，配偶受孕率78．8％；对照组总有效率为54．2％，配偶受孕率43．4％，两组比较差异有非常显著性意义（P〈0．01）两组生殖内分泌激素治疗后均有明显改善（P〈0．01）治疗组治疗后精浆超氧化物歧化酶、微量元素锌显著增加，而镉明显下降，与治疗前比较差异有显著性意义（P〈0．05）。结论：针挑治疗原发性精子异常有显著改善和调节内分泌功能、提高精子与精浆质量、提高妊娠率的作用，是目前治疗本病非药物疗法中的较佳疗法。

Clinical observation and study of mechanisms of needle-picking therapy for primary infertility of abnormal sperm

OBJECTIVE: To search for the best method for increasing clinical therapeutic effect on primary abnormality of sperm. METHODS: One hundred and sixty-eight cases of infertility were randomly divided into a treatment group of 85 cases and a control group of 83 cases. The treatment group were treated with needle-picking at bilateral Shengzhi points, Dicong Shenjing points and L2 Shenjing points as main. The control group were treated with oral administration of Wuzi Yanzong Pills symbol: see text]. Their therapeutic effects were observed in 3 hospitals. RESULTS: The total effective rate of 83.5% and the pregnancy rate of the patient's wife of 78.8% in the treatment group, and corresponding figures were 54.2% and 43.4% in the control group, with a very significant difference between the two groups (P < 0.01); and reproductive hormones improved significantly after treatment in the two groups (P < 0.01); after treatment, superoxide dismulase (SOD) activity and Zn content in semen were elevated and cadmium level decreased significantly in the treatment group (P < 0.05). CONCLUSION: Needle picking therapy can significantly improve and regulate endocrine function, increase quality of semen and elevate pregnancy rate of the patient's wife for the patient of primary abnormal sperm.