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Metastatic melanoma to the common bile duct causing obstructive jaundice: A case report
引用本文:Colovic RB,Grubor NM,Jovanovic MD,Micev MT,Colovic NR. Metastatic melanoma to the common bile duct causing obstructive jaundice: A case report[J]. World journal of gastroenterology : WJG, 2007, 13(5): 813-815. DOI: 10.3748/wjg.v13.i5.813
作者姓名:Colovic RB  Grubor NM  Jovanovic MD  Micev MT  Colovic NR
作者单位:Radoje B Colovic(Institute for Digestive Diseases, First Surgical Clinic, Clinical Center of Serbia, Koste Todoroviea 6, Belgrade 11000, Serbia) ;Nikica M Grubor(Institute for Digestive Diseases, First Surgical Clinic, Clinical Center of Serbia, Koste Todoroviea 6, Belgrade 11000, Serbia) ;Miodrag D Jovanovic(Institute for Digestive Diseases, First Surgical Clinic, Clinical Center of Serbia, Koste Todoroviea 6, Belgrade 11000, Serbia) ;Marjan T Micev(Institute for Digestive Diseases, First Surgical Clinic, Clinical Center of Serbia, Koste Todoroviea 6, Belgrade 11000, Serbia) ;Natasa R Colovic(Institute for Digestive Diseases, First Surgical Clinic, Clinical Center of Serbia, Koste Todoroviea 6, Belgrade 11000, Serbia) ;
摘    要:
Metastatic melanoma to the common bile duct is very rare with only 18 cases reported so far. We report a 46 year old women who, 18 mo after excision of a skin melanoma, developped a painless progressive obstructive jaundice. At operation a melanoma within the distal third of the common bile duct was found. There were no other secondaries within the abdomen. The common bile duct, including the tumor, was resected and anastomosed with Roux-en-Y jejunal limb. The patient survived 31 mo without any sign of local recurrence and was submitted to three other operations for axillar and brain secondaries, from which she finally died. Radical resection of metastatic melanoma to the common bile duct may result in lifelong relief of obstructive jaundice. It is safe and relatively easy to perform. In other cases, a less aggressive approach, stenting or bypass procedures, should be adopted.

关 键 词:黑色素瘤  胆管  肿瘤转移  阻塞性黄疸  病例报告
收稿时间:2006-10-10

Metastatic melanoma to the common bile duct causing obstructive jaundice: a case report
Colovic Radoje B,Grubor Nikica M,Jovanovic Miodrag D,Micev Marjan T,Colovic Natasa R. Metastatic melanoma to the common bile duct causing obstructive jaundice: a case report[J]. World journal of gastroenterology : WJG, 2007, 13(5): 813-815. DOI: 10.3748/wjg.v13.i5.813
Authors:Colovic Radoje B  Grubor Nikica M  Jovanovic Miodrag D  Micev Marjan T  Colovic Natasa R
Affiliation:Institute for Digestive Diseases, First Surgical Clinic, Clinical Center of Serbia, Koste Todoroviea 6, Belgrade 11000, Serbia
Abstract:
Metastatic melanoma to the common bile duct is very rare with only 18 cases reported so far. We report a 46 year old women who, 18 mo after excision of a skin melanoma, developped a painless progressive obstructive jaundice. At operation a melanoma within the distal third of the common bile duct was found. There were no other secondaries within the abdomen. The common bile duct, including the tumor, was resected and anastomosed with Roux-en-Y jejunal limb. The patient survived 31 mo without any sign of local recurrence and was submitted to three other operations for axillar and brain secondaries, from which she finally died. Radical resection of metastatic melanoma to the common bile duct may result in lifelong relief of obstructive jaundice.It is safe and relatively easy to perform. In other cases, a less aggressive approach, stenting or bypass procedures,should be adopted.
Keywords:Metastatic melanoma  Common bile duct  Jaundice
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