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XELOX方案治疗晚期胃癌的临床研究
引用本文:杨志敏,王潞,吉兆宁. XELOX方案治疗晚期胃癌的临床研究[J]. 安徽医学, 2011, 32(3): 283-285. DOI: 10.3969/j.issn.1000-0399.2011.03.011
作者姓名:杨志敏  王潞  吉兆宁
作者单位:皖南医学院附属弋矶山医院肿瘤防治中心,芜湖,241001;皖南医学院附属弋矶山医院肿瘤防治中心,芜湖,241001;皖南医学院附属弋矶山医院肿瘤防治中心,芜湖,241001
摘    要:
目的 观察奥沙利铂联合希罗达治疗晚期胃癌的疗效及毒副作用.方法 L-OHP 130 mg/m2,加入5%GS 500ml中静脉滴注2 h,第1d,Xeloda 1 000 mg/m2,2次/d,口服,第1~14 d,21 d为1周期,连用2个周期后评价疗效.结果 CR1例,PR 12例,SD 8例,PD 8例,有效率为...

关 键 词:胃肿瘤  奥沙利铂  希罗达  药物疗法

Clinical study on XELOX regimen in treatment of advanced gastric cancer
Yang Zhimin,Wang Lu,Ji Zhaoning. Clinical study on XELOX regimen in treatment of advanced gastric cancer[J]. Anhui Medical Journal, 2011, 32(3): 283-285. DOI: 10.3969/j.issn.1000-0399.2011.03.011
Authors:Yang Zhimin  Wang Lu  Ji Zhaoning
Affiliation:Yang Zhimin,Wang Lu,Ji Zhaoning Department of Tumour Prevention and Treatment Centre,Yijishan Hospital of Wannan Medical College,Wuhu 241001,China
Abstract:
Objective To evaluate the efficacy and toxicity of Oxaliplatin combined with Xeloda(XELOX) in the treatment of advanced gastric cancer.Methods 29 patients with advanced gastric cancer received intravenous infusion of Oxaliplatin at the dose of 130 mg/m2 on day 1,and oral administration of Xeloda at1 000 mg/m2 twice a day on days 1~14.The chemotherapy was repeated every 21 days and the efficacy was evaluated after 2 cycles.Results The overall response rate was 44.8%(13/29).One of 29 patients achieved a compl...
Keywords:Stomach neoplasms  Oxaliplatin  Xeloda  Drug therapy  
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