| 恶性肿瘤住院患者合并铜绿假单胞菌感染及耐药性分析 |
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| 引用本文： | 杨桐树,梁影,钟志,彭国睿,李文辉,梁天孚. 恶性肿瘤住院患者合并铜绿假单胞菌感染及耐药性分析[J]. 中国卫生检验杂志, 2011, 0(8) |
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| 作者姓名： | 杨桐树 梁影 钟志 彭国睿 李文辉 梁天孚 |
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| 作者单位： | 哈尔滨医科大学附属第三医院检验科; |
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| 摘 要： | 目的:探讨我院恶性肿瘤住院患者合并铜绿假单胞菌(PAE)感染的耐药情况,为临床合理用药提供科学依据。方法:细菌鉴定采用手工法和美国MicroScan WalkAway40SI全自动微生物分析仪进行。药敏试验采用K-B纸片扩散法,用WHONET5.4软件进行统计分析。结果:本研究共检出G-杆菌2889株,其中PAE 254株(8.8%);PAE感染有逐年上升趋势(P<0.05)。PAE感染主要集中于内科、放疗和ICU等科室;PAE对环丙沙星的耐药率最低(8.3%)、其次为头孢哌酮/舒巴坦(10.2%)、头孢他啶(11.0%)、阿米卡星(11.4%)、美洛培南(11.8%)、哌拉西林/他唑巴坦(13.4%)、亚胺培南(14.2%)、头孢吡肟(14.2%)、左氧氟沙星(14.6%)等,而对复方新诺明的耐药率最高(95.3%)。结论:PAE是我院恶性肿瘤住院患者合并感染的主要病原菌之一,对多种抗菌药物均产生不同程度的耐药性。
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| 关 键 词： | 恶性肿瘤患者 铜绿假单胞菌 耐药性 |
Analysis of the Pseudomonas aeruginosa infection and antibiotic resistance in patients with malignant tumor |
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| YANG Tong-shu,LIANG Ying,ZHONG Zhi,PENG Guo-rui,LI Wen-hui,LIANG Tian-fu. Analysis of the Pseudomonas aeruginosa infection and antibiotic resistance in patients with malignant tumor[J]. Chinses Journal of Health Laboratory Technology, 2011, 0(8) |
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| Authors: | YANG Tong-shu LIANG Ying ZHONG Zhi PENG Guo-rui LI Wen-hui LIANG Tian-fu |
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| Affiliation: | YANG Tong-shu,LIANG Ying,ZHONG Zhi,PENG Guo-rui,LI Wen-hui,LIANG Tian-fu(Department of laboratory,The Third Affiliated Hospital of Harbin Medical University,Harbin 150081,China) |
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| Abstract: | Objective:To provide scientific basis for clinical rational drug use in our hospital through exploration on drug resistance of inpatients with malignant tumors complicated with pseudomonas aeruginosa infection.Methods:Identification of bacteria was realized by using manual method and the U.S.MicroScan WalkAway40SI automatic microorganism analyzer.Drug sensitivity test was done by K-B disk diffusion method with WHONET5.4 software for statistical analysis.Results:2889 strains were detected with G-bacillus,inc... |
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| Keywords: | Malignant tumor patient Pseudomonas aeruginosa Drug resistance |
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