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| 食管癌,大肠癌血卟啉变化及其意义 | |
| 引用本文： | 李少华 郝英华. 食管癌,大肠癌血卟啉变化及其意义[J]. 中国肿瘤临床, 1998, 25(12): 878-880 |
| 作者姓名： | 李少华 郝英华 |
| 作者单位： | 哈尔滨医科大学附属二院，哈尔滨铁路中心医院，哈尔滨医科大学生物物理教研室 |
| 摘 要： | 采用紫外光激光技术，对３９例食管癌，４１例大肠癌血卟啉分子荧光光谱进行检测。分别与４５例慢性食管炎，３１例慢性结肠炎及１６例大肠息肉做对照，发现癌肿组锌卟啉及原卟啉较对照组明显升高，特别是原卟啉峰增高３倍以上，差别有极显著意义（Ｐ＜０．０１），原卟啉可做为肿瘤血液标记物，对食管癌大肠癌进行诊断 |
| 关 键 词： | 食管癌 卟啉类 血液 大肠癌 |
Significance of Hematoporphyrin Changes in Patients with Carcinoma of Esophagus and Large Intestine |
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| Li Shaohua Hao Yinghua Gao Shanling et al Second Hospital,Harbin Medical University,Harbin. Significance of Hematoporphyrin Changes in Patients with Carcinoma of Esophagus and Large Intestine[J]. Chinese Journal of Clinical Oncology, 1998, 25(12): 878-880 | |
| Authors: | Li Shaohua Hao Yinghua Gao Shanling et al Second Hospital Harbin Medical University Harbin |
| Abstract: | The fluorescence spectroscopy of porphyrin modecule in blood was determined with ultraviolet spectroscopy in 39 patients with esophageal cancer, 41 with cancer of large intestine, 45 with chronic esophagitis,31 with chronic colitis, and 16 with polyps of large intestine as control. The results showed that the peaks of zinc porphyrin and protoporphyrin in patients with cancer were significantly higher than those in patients with benign diseases and that the peak of protoporphyrin was three times higher in the former patient groups than the latter ( P <0.01). Therefore, protoporphyrin could be used as a marker to screen and diagnose cancer of esophagus and large intestine. |
| Keywords: | Esophageal carcinoma Porphyrin Blood Carcinoma of large intestine |
| 本文献已被 CNKI 维普 等数据库收录！ | |