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泼尼松联合环孢素A治疗干燥综合征合并血小板减少的临床观察
引用本文:王燕,吕保良,王少亭,王琰,杨宏,张燕. 泼尼松联合环孢素A治疗干燥综合征合并血小板减少的临床观察[J]. 中华全科医师杂志, 2005, 8(1): 486-488. DOI: 10.3760/cma.j.issn.1671-7368.2009.07.022
作者姓名:王燕  吕保良  王少亭  王琰  杨宏  张燕
作者单位:河南郑州大学第五附属医院肾病风湿科,450052;郑州铁路职业技术学院医技系;
摘    要:
Thirty patients with confirmed primary sjogren syndrome and thrombocytopenia during January 2002 and December 2007 were investigated.All the participants received 0.5 mg·kg-1·d-1 Prednisone and 100 ms/d CosA for 1 year.Clinical symptoms and the levels of white blood eell.platelet count,erythrocyte sedimentation rate,liver function,immunoglobin,and rheumatoid factors were recored before and after the treatment.After one-year follow.up,platelet count was elevated(t=11.4179,P< 0.01).There was no significant change in erythrocyte sedimentation rate.The concentrations of immunoglobin and rheumatoid factors were significantly decreased at 1 year(t=5.4222,P<0.01;t= 9.2857.P<0.01).Prednisone plus CosA could effectively treat primary sjOgren syndrome combined with thrombocytopenia and result in fewer side effects.

关 键 词:干燥综合征   血小板减少   

Effects of CosA plus Prednisone in the treatment of primary sjogren syndrome combined with thrombocytopenia
WANG Yan,LV Bao-liang,WANG Shao-ting,WANG Yan,YANG Hong,ZHANG Yan. Effects of CosA plus Prednisone in the treatment of primary sjogren syndrome combined with thrombocytopenia[J]. Chinese JOurnal of General Practitioners, 2005, 8(1): 486-488. DOI: 10.3760/cma.j.issn.1671-7368.2009.07.022
Authors:WANG Yan  LV Bao-liang  WANG Shao-ting  WANG Yan  YANG Hong  ZHANG Yan
Abstract:
Keywords:Sjogren's syndromeThrombocytopenia
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