阿托品在无痛人流术中的临床应用

目的探讨阿托品抗异丙酚和芬太尼的副作用和防止人流综合症及术后腹痛的可能机制。方法选择1000例孕期在40~80d自愿要求无痛人流的孕妇随机分为观察组和对照组,观察组在实施无痛人流中使用阿托品,比较两组人流综合征的发生率和术后镇痛效果。结果阿托品在无痛人流中能够有效防止人流综合征的发生,并能减轻术后腹痛。结论阿托品能有效桔抗异丙酚和芬太尼引发的呼吸、循环抑制,从而防止呼吸减慢、心动过缓、血压下降以及术后恶心呕吐、腹痛的发生,有利于保证手术质量和安全性,可推广应用。

Application of atropine in painless induced abortion

Objective To explore the underlying mechanism in which atropine mitigates the side-effects of propofol and fentanyl and prevents induced abortion syndrome and postoperative bellyache. Methods 1000 pregnant volunteers with the gestational period of 40 to 80 days were divided into control and observation groups. Atropine was used in observation group but not in control group to compare the incidence of induced abortion syndrome and the postoperative analgesic effect between the two groups. Results Atropine has been found to effectively prevent induced abortion syndrome and reduce postoperative bellyache. Conclusion Atropine is favored because it can effectively impede respiration and circulation suppression caused by propofol and fentanyl, and thereupon enhances the safety of the operation.