部分变应性因素与慢性鼻-鼻窦炎的临床相关性研究

目的：探讨变应性因素在慢性鼻-鼻窦炎（CRS）发病过程中的作用。方法：分析194例CRS患者术前血清变应原检测（TIgE、SIgE）及变应原皮肤点刺试验（SPT）结果，并与临床分型进行比较。结果：①主要变应原分布：屋尘阳性率20．6％（40／194），粉尘螨阳性率16．0％（30／194），屋尘螨阳性率14．9％（29／194）；②CRS实验组与正常对照组屋尘螨、粉尘螨、屋尘SIgE、SPT阳性率比较有统计学意义；③CRS实验组屋尘螨、粉尘螨、屋尘SIgE与临床分型呈负相关，差异有统计学意义。结论：部分变应性因素与CRS的病因及病程有关。

The study of correlation between allergen and chronic rhinosinusitis

Objective:To explore the effects of allergic factors in chronic sinusitis . Method:Skin prick test and specific serum IgE of 194 patients with chronic sinusitis were performed in our department before endoscopic sinus surgery from October,2007 to October,2008, and correla- tion between test results and clinical classification was analyzed retrospectively. Result: ① Result of skin prick test was analyzed. Positive rate of house dust was 20.6% (40/194),of dust mites 16.0%(30/194),of house dust mites 14.9%(29/194). ② Positive rate of allergic specific serum IgE and skin prick test in experimental group was compared with that of control group. Positive rate of house dust mites,dust mites and house dust between groups were significantly different(P<0.05).③ Clinical classification of chronic sinusitis had a negative correlation with the specific serum IgE (house dust mites ,house dust and dust mites)about experimental group(P<0.05). Conclusion: Allergic factors was associated with etiopathoge-nisis and course of disease of chronic sinusitis.