软组织感染不同时相磁共振病理研究

目的 探讨软组织感染MRI信号特点及其与病理间关系。方法 14只免子肌肉注入松节油后即刻、1、3、5、7、10、14、19、27、36d分别选4只行MRI成像,每次在4只中选1只行病理检查。结果 即刻T1WI为片状模糊低信号,T2WI高信号;10dT1WI为高信号环,T2WI为低信号环;10-36d境界变清,环增厚,环内T1WI低信号,以后逐渐增高,T2WI信号7-10d最高,以后减低。病理主要为水肿、炎性细胞浸润、组织坏死、脓肿形成。结论 MRI是诊断软组织成染最好影像学检查方法之一。

Pathological basis of soft tissue infection on MRI

Objective To explore the signal change patterns on MRI, and the relation between the signal change of MRI and pathological change of soft tissue infection. Methods Soft tissue infection models on 14 rabbits were set up and randomly selected four rabbits to image with MRI immediately and then repeated on 1st, 3rd, 5th, 7th, 10th, 14th, 19th, 27th, 36th days after injecting turpentine in muscles. Randomly selected one rabbit from 4 rabbits was sacrificed to obtain tissue samples for pathological studies every time. Results The signals immediately on T1WI became lower, on T2WI became high and the margin was blur after injecting turpentine in muscles. It became hyperintense rim on T1WI and hypointense rim on T2WI on the tenth day. The signal intensity in the rim became lower on T1WI and got up to the peak from 7th to 10th days on T2WI. The margin became more sharper from 10th to 36th days. The rim became thicker. The signal intensity in the rim became more higher on T1WI and lower on T2WI. The pathological changes were edema, infiltration of inflammatory cells, tissue necrosis and abscess. Conclusion MRI is one of the best imaging modality for soft tissue infection.