Quercetin and naringenin; effects on ulcer formation and gastric secretion in rats |
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| Authors: | M. J. Martin,V. Motilva,C. Alarc
N de la Lastra |
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| Affiliation: | M. J. Martin,V. Motilva,C. Alarc ÓN de la Lastra |
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| Abstract: | ![]()
The antiulcerogenic effect of two flavonoids, quercetin and naringenin, in acute gastric ulcer (cold-restraint and pylorus-ligated) has been investigated. In both models quercetin and naringenin presented a significant decrease in ulcer index with respect to the control group. Nevertheless, in the Shay-ligated method no decrease in either volume, acidity or pepsin were observed, however, a significant difference was found in histamine secretion values. |
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| Keywords: | Flavonoids antiulcer activity gastric secretion stress ulcer |
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