血常规参数在SARS-CoV-2感染确诊患者、疑似患者、甲型及乙型流感患者中诊断与鉴别诊断的意义

目的了解新型冠状病毒(SARS-CoV-2)感染初期血常规特点,分析SARS-CoV-2感染确诊患者、疑似患者、甲型及乙型流感患者血常规等指标,为早期临床诊断治疗提供依据。方法回顾性分析2019年11月至2020年2月该院发热门诊就诊患者,通过诊断标准将其分为SARS-CoV-2感染确诊患者、疑似患者、甲型及乙型流感患者,对4组患者进行血常规筛查,选择有鉴别意义的标志物。结果该研究纳入发热门诊发热待查患者91例,其中SARS-CoV-2感染确诊患者9例,疑似患者31例,甲型流感患者31例,乙型流感患者20例。SARS-CoV-2感染确诊患者与另外3组相比,白细胞与血小板为有鉴别意义的生物标志物,与流感患者相比,淋巴细胞同样为有鉴别意义的生物标志物。结论血常规参数在SARS-CoV-2感染确诊患者、疑似患者、甲型及乙型流感患者中诊断与鉴别诊断具有一定的意义,可以作为核酸检测的重要补充。

Significance of blood routine biomarkers in the diagnosis and differential diagnosis of patients with SARS-Cov-2 infection,suspected patients and patients with influenza A and B

Objective To evaluate the severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection in the early stage of blood routine characteristics,to identify SARS-CoV-2 infection confirmed patients,suspected patients,influenza A and B blood routine indicators,provide evidence for early clinical diagnosis and treatment.Methods A retrospective analysis was performed on the patients who visited the hospital from November 2019 to February 2020.They were divided into patients diagnosed with SARS-CoV-2 infection,suspected patients,and patients with influenza A and B by the diagnostic criteria.Patients were screened for routine blood and selected markers that were of significant significance.Results This study included 91 patients totally,including 9 confirmed SARS-CoV-2 infection patients,31 suspected SARS-CoV-2 infection patients,31 patients with influenza A,20 patients with influenza B,and compared with the other three groups,white blood cells and platelets were statistically differentiating biomarkers.Compared with influenza patients,lymphocyte counts were also statistically significant biomarkers.Conclusion Blood routine biomarkers have certain significance in the diagnosis and differential diagnosis of SARS-CoV-2 infected patients,suspected patients,influenza A and B patients,and can be used as a supplement with effect for nucleic acid detection.