糖网灵治疗糖尿病视网膜病变临床观察

目的:观察糖网灵治疗糖尿病视网膜病变的临床疗效。方法:将60例确诊为糖尿病视网膜病变的患者随机分为2组。治疗组给予自拟糖网灵中药煎剂治疗;对照组应用导生明口服,疗程均为4周。结果:治疗组显效11例,有效15例,无效4例,总有效率为86.67%(95%CI=71.00%~96.50%);对照组显效9例,有效12例,无效9例,总有效率70.00%(95%CI=53.60%~86.40%);两组综合疗效比较(u=1.094 8,P0.05),差异无显著性意义。结论:糖网灵治疗糖尿病视网膜病变疗效优于导生明的证据不充分,其收益为OR=0.36(95%CI=0.10~1.33),NNT=6(95%CI=2.67~29.87)。

Clinical Observation of Tang-wang-ling on Diabetic Retinopathy

Objective： To observe the clinical effect of Tang-wang-ling on diabetic retinopathy. Methods： 60 cases with diabetic retinopathy were randomly divided into 2 groups. Treatment group was given to the decoction of Tang-wang-ling, and control group was given to Dao-sheng-ming orally taken. One course of treatment included 4 weeks. Results： In treatment group 11 cases were excellent, 15 ones effective, and 4 ones ineffective. The total effective rate was 86.67% （95% CI =71.00% -96.50% ）. In control group 9 cases were excellent, 12 ones ef- fective, and 9 ones ineffective. The total effective rate was 70.00% （95% CI =53.60% -86.40% ）. There was no significant differences between the two groups （ u = 1. 094 8 ,P 〉 0.05 ）, NNT = 6 （95% CI = 2.67 - 29.87 ） o Conclusion： There is not enough evidence to show that Tang-wang-ling has better effect than Dao-sheng-ming on diabetic retinopathy, OR =0.36 （95%CI =0.10 - 1.33）, NNT =6 （95%CI =2.67 -29.87）.