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冠脉轻度狭窄患者内皮功能和冠脉血流储备的临床观察
引用本文:张勇,王人彭,王新宇,骆秉铨,唐小霞,陈青远,陈兴新. 冠脉轻度狭窄患者内皮功能和冠脉血流储备的临床观察[J]. 微循环学杂志, 2011, 21(3): 46-48,89,92
作者姓名:张勇  王人彭  王新宇  骆秉铨  唐小霞  陈青远  陈兴新
作者单位:1. 徐州市肿瘤医院心内科,徐州,221009
2. 中国矿业大学生物医学工程系
基金项目:江苏省徐州市科技局课题资助
摘    要:
目的:观察冠脉轻度狭窄患者血管内皮功能和冠脉血流储备(CFR)的变化。方法:常规冠脉造影显示冠脉狭窄<50%患者56例,根据冠脉内注射乙酰胆碱(Ach)反应结果分为Ach阳性组与阴性组;运用数字跟踪技术软件测算两组患者CFR,并采血检测超敏C-反应蛋白(hs-CRP)水平。结果:Ach阳性组CFR低于阴性组(P<0.05),hs-CRP高于阴性组(P<0.01)。结论:早期冠心病患者存在内皮功能异常且伴有CFR降低。

关 键 词:内皮功能  冠脉血流储备  冠心病

Clinical Research on Endothelial Function and Coronary Flow Reserve in Patients with Mild Coronary Stenosis
Zhang Yong,Wang Renpeng,Wang Xinyu,et al/. Clinical Research on Endothelial Function and Coronary Flow Reserve in Patients with Mild Coronary Stenosis[J]. Chinese Journal of Microcirculation, 2011, 21(3): 46-48,89,92
Authors:Zhang Yong  Wang Renpeng  Wang Xinyu  et al/
Affiliation:Zhang Yong,Wang Renpeng,Wang Xinyu,et al/Department of Cardiology,Cancer Hospital of Xuzhou City,Xuzhou 221009
Abstract:
Objective: To explore the relationship between endothelial dysfunction and reduced coronary flow reserve(CFR) by conventional coronary angiography.Method: Endothelial dysfunction of 56 patients with suspected coronary artery disease and coronary stenosis <50% by coronary angiography were evaluated by intracoronary injection of acetylcholine(Ach).According to Ach test,they were divided into positive and negative groups.CFR was measured by the use of digital tracking software and high-sensitivity C-reactive p...
Keywords:Endothelial dysfunction  Coronary flow reserve  Coronary artery disease  
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