| 槌果藤提取物对银屑病样小鼠模型作用的实验研究 |
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| 引用本文： | 华伟,李凡,惠艳,米新陵,杨克健. 槌果藤提取物对银屑病样小鼠模型作用的实验研究[J]. 中国中西医结合皮肤性病学杂志, 2008, 7(3): 138-141 |
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| 作者姓名： | 华伟 李凡 惠艳 米新陵 杨克健 |
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| 作者单位： | 1. 克拉玛依市中心医院,克拉玛依,834000
2. 新疆医科大学第一附属医院,乌鲁木齐,830054 |
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| 摘 要： | 目的观察槌果藤提取物外用对银屑病样小鼠模型的影响。方法槌果藤提取物外涂小鼠尾部鳞片21d后．取鼠尾组织病理检查及雌激素周期小鼠阴道灌注4d，取阴道组织病理检查，两组均设有阴、阳性对照。结果95％乙醇提取物和他扎罗汀对小鼠尾部鳞片表皮颗粒层形成具有明显促进作用．对雌性周期小鼠阴道上皮细胞分裂指数有明显抑制作用。结论槌果藤95％乙醇提取物具有抗银屑病作用。
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| 关 键 词： | 槌果藤 银屑病 动物模型 |
Topical Administration of Capparis Spinosa L Extract on Mice''s Psoriasis Like Animal Models |
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| HUA Wei,LI Fan,Hiu Yan,MI Xin-ling,YANG Ke-jian. Topical Administration of Capparis Spinosa L Extract on Mice''s Psoriasis Like Animal Models[J]. Chinese J of Dermatovenerology Integr Tradit and West Med, 2008, 7(3): 138-141 |
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| Authors: | HUA Wei LI Fan Hiu Yan MI Xin-ling YANG Ke-jian |
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| Affiliation: | HUA Wei, LI Fan, HU1 Yan, Ml Xin-lin, YANG Ke-jia(1. The Central Hospital of Kalamayi, Kalamayi 834000, China;2. The First Affiliated Hospital of X injiang Medical University, Urumqi 830054, China) |
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| Abstract: | Objective To investigate the effects of Capparis spinosa L extract in topical treatment on mice＇s psoriasis like animal models. Methods The effect of Capparis spinosa L extract on granular layer mouse tail scale epidermis and the epithelial mitosis were observed by Longitudinal histological sections prepared from the tail skin and vaginal epithelium. Results Both ethanols extract and Tazalotine Gel possessed significant inhibiting effect on mouse vaginal epithelial mitosis and significant promoting effect on the formation of granular layer in mouse tail scale epidermis. Conclusion Capparis spinosa L extract of ethanol might be popential in topical treatment of psoriasis. |
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| Keywords: | Capparis spinosa L psoriasis animal models |
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