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| 板式组合药在治疗肺结核时的不良反应与患者体质量分析 | |
| 引用本文： | 陈瑜晖,温良焕,蒋莉,尹建军,温梅云. 板式组合药在治疗肺结核时的不良反应与患者体质量分析[J]. 武警医学院学报, 2010, 19(2): 117-119,122 |
| 作者姓名： | 陈瑜晖 温良焕 蒋莉 尹建军 温梅云 |
| 作者单位： | 广东省结核病防治研究所,广东,广州,510630 |
| 摘 要： | 【目的】探讨板式组合药在初治涂阳肺结核患者应用中的不良反应与患者体质量的关系。【方法】对273例确诊的初治涂阳肺结核患者,采用短程化疗方案,用抗结核板式组合药进行治疗并观察不良反应。【结果】患者在应用抗结核板式组合药的治疗过程中出现不良反应症状共114例,占全部病例的41.76%,发生不良反应的患者中以体质量低于标准体质量者居多,占76.32%。低于标准体质量组的患者与正常或高于标准体质量者在总反应、胃肠道反应、肝损害、尿酸增高及关节痛方面存在显著性差异（P〈0.05）;而在血液有形成分、神经系统反应及其它方面无差别（P〉0.05）。【结论】低于标准体质量的患者在服用抗结核板式组合药时更容易发生不良反应。在应用板式组合药时应考虑到患者的体质量因素。 |
| 关 键 词： | 结核 肺 药物治疗 不良反应 体质量 |
Analysis on adverse drug reactions of blister pack drug in treating pulmonary tuberculosis and body mass index |
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| CHEN Yu-hui,WEN Liang-huan,JIANG Li,YIN Jian-jun,WEN Mei-yun. Analysis on adverse drug reactions of blister pack drug in treating pulmonary tuberculosis and body mass index[J]. Acta Academiae Medicinae CPAPF, 2010, 19(2): 117-119,122 | |
| Authors: | CHEN Yu-hui WEN Liang-huan JIANG Li YIN Jian-jun WEN Mei-yun |
| Affiliation: | CHEN Yu-hui,WEN Liang-huan,JIANG Li,YIN Jian-jun,WEN Mei-yun(Antituberculosis Research Institute of Guangdong Province,Guangzhou 510630,China) |
| Abstract: | [Objective]To explore the relation of adverse drug reactions(ADRs)of the new smear-positive pulmonary tuberculosis patients(PTB)and their body quality in using the blister pack.[Methods]273 PTB received short-course chemotherapy with blister pack and their adverse reactions were recorded.[Results]Of 273 patients,114 cases experienced ADRs.Among them 76.32% were with infra-BMI(body mass index).Significant difference was found between the infra-BMI group and the normal or super-BMI group in overall reaction,g... |
| Keywords: | Tuberculosis pulmonary Drug therapy Adverse drug reactions Body mass index |
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