干扰素治疗小儿呼吸道感染的研究

目的观察干扰素治疗小儿呼吸道感染的疗效。方法将90例呼吸道感染的小儿随机分成3组,在对症治疗基础上,A组静脉点滴利巴韦林10mg/(kg·d),B组肌注干扰素10μg,1次/d,C组空气压缩泵雾化吸入干扰素10μg,1次/d,观察3组的病情变化。结果C组咳嗽、发热、喘憋及肺部体征好转时间均较A组明显缩短(P<0.01),B组与C组疗效无显著性差异。结论干扰素治疗小儿呼吸道感染疗效确切,值得推广。

Study of interferon on children respiratory infection

Objective It is to observe the curative effect of interferon on children respiratory infection. Methods 90 patients with children respiratory infection were randomly divided into three groups. Based on symptomatic treatment, group A was treated with intravenous drip Ribavirin 10 mg/(kg·d), group B was treated with intramuscular injection interferon 10 μg once a day and group C was treated with air compressor atomization inspire interferon 10 μg once times a day. The changes of pathogenetic condition in the three groups were observed. Results The improving times of cough, fever, wheezer rale and lung signs in group C were all obviously shorter than that in group A (P<0.01). The curative effects have no significant difference between group C and group B. Conclusion Interferon is effective on children respiratory infection.