| 肿瘤相关成纤维细胞与肿瘤发生及演进关系的研究进展 |
| |
| 引用本文： | 苏林,辛彦.肿瘤相关成纤维细胞与肿瘤发生及演进关系的研究进展[J].现代肿瘤医学,2011,19(11):2337-2340. |
| |
| 作者姓名： | 苏林 辛彦 |
| |
| 作者单位： | 中国医科大学附属第一医院肿瘤研究所胃肠肿瘤病理研究室,辽宁,沈阳,110001 |
| |
| 基金项目： | 国家自然科学基金资助项目，教育部高等学校博士学科点专项科研基金，沈阳市科学技术计划项目 |
| |
| 摘 要： | 作为肿瘤间质的主要细胞成分,肿瘤相关成纤维细胞(tumor-associated fibroblasts,TAFs)与正常组织间质成纤维细胞(fibroblasts)的生物学特性差异明显。TAFs在肿瘤的发生及演进过程中起着重要的作用,关于这方面的研究日益成为热点。本文就TAFs与肿瘤发生及演进关系的研究进展做一综述。
|
| 关 键 词： | 肿瘤相关成纤维细胞 肿瘤 发生 演进 |
Research progress of the relationship of tumor-associated fibroblasts and tumor initiation and progression |
| |
| SU Lin,XIN Yan.Research progress of the relationship of tumor-associated fibroblasts and tumor initiation and progression[J].Journal of Modern Oncology,2011,19(11):2337-2340. |
| |
| Authors: | SU Lin XIN Yan |
| |
| Institution: | SU Lin,XIN Yan Gastrointestinal Tumor Pathology Laboratory of Cancer Institute,Department of Tumor Pathology of General Surgery Institute,No.1 Hospital of China Medical University,Shenyang 110001,China |
| |
| Abstract: | As the predominant cells in the tumor stroma,tumor-associated fibroblasts(TAFs)are significantly different from normal tissue fibroblasts in the biological features.TAFs play a critical role in tumor initiation and progression,which is in the spot light.This review reports the progress in the study on corralation of TAFs with tumor initiation and progression. |
| |
| Keywords: | tumor-associated fibroblasts(TAFs) tumor tumorigenesis progression |
| 本文献已被 CNKI 万方数据 等数据库收录！ |
