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| 吡啶斯的明试验对评价垂体hGH储备功能的价值 | |
| 引用本文： | 王晓东,潘长玉. 吡啶斯的明试验对评价垂体hGH储备功能的价值[J]. 中华内分泌代谢杂志, 1990, 0(4) |
| 作者姓名： | 王晓东 潘长玉 |
| 作者单位： | 中国人民解放军总医院内分泌科(王晓东)，中国人民解放军总医院内分泌科(潘长玉) |
| 摘 要： | 作者试用胆碱酯酶抑制剂吡啶斯的明兴奋hGH释放,并与胰岛素兴奋hGH试验作比较,观察了13例正常青少年和8例垂体性侏儒症患者对两种兴奋试验的反应。结果显示口服吡啶斯的明2mg/kg体重能迅速有效地兴奋垂体hGH释放,其作用较胰岛素兴奋试验更为强大,是一项值得推荐的判定青少年垂体hGH储备功能的试验。 |
| 关 键 词： | 垂体生长激素 吡啶斯的明 胰岛素 侏儒症 |
THE VALUE OF PYRIDOSTIGMINE IN EVALUATION OF GH RESERVE IN CHILDREN AND ADOLESCENTS |
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| Wang Xiao-dong Pan Chang-yuDept. of Endocrinology,Chinese PLA General Hospital. THE VALUE OF PYRIDOSTIGMINE IN EVALUATION OF GH RESERVE IN CHILDREN AND ADOLESCENTS[J]. Chinese Journal of Endocrinology and Metabolism, 1990, 0(4) | |
| Authors: | Wang Xiao-dong Pan Chang-yuDept. of Endocrinology Chinese PLA General Hospital |
| Abstract: | In the present study, we observed the effects of cholinergic enhancement by pyridostigmine (PD), a cholinesterases inhibitor, on GH release in both normal (n = 13) and GH deficient children and adolescents (n = 8). Responses of GH to insulin hypoglycemia were also observed. In the normal subjects, PD-induced serum GH peak levels were significantly higher than that induced by insulin (P<0.0l). By contrast, the GH level in the patients with pituitary dwarfism showed no increase by both tests. The study indicates that PD test may be considered as a sensitive dynamic test in evaluating pituitary function of GH secretion in children and adolescents. |
| Keywords: | Growth hormone Pyridostigmine Insulin Dwarfism |
| 本文献已被 CNKI 等数据库收录！ | |