首页 | 本学科首页   官方微博 | 高级检索  
     


Prevalence of peripheral neuropathy in patients with diabetes: A systematic review and meta-analysis
Affiliation:1. Pfizer, Inc., New York, NY, USA;2. Outcomes Research Consultant, New York, NY, USA;3. Translational Pain Research Program, Department of Neurosurgery, University of Rochester Medical Center, Rochester, NY, USA
Abstract:
AimsWe aimed to determine pooled prevalence of diabetic peripheral neuropathy (DPN) in patients with diabetes and to explore the impacts of research variables on prevalence estimates.MethodsA systematic search was performed in PubMed, EMBASE, The Cochrane Library and Scopus from onset up to July 2018 to identify articles investigating the prevalence of DPN. Random-effects models were used to calculate the pooled prevalence of DPN. The heterogeneity of the study was estimated with the I2 statistic. The publication bias was described by Egger’s test and funnel plot.ResultsA total of 29 studies with a total of 50,112 participants were included in this meta-analysis. The results showed that the pooled prevalence of DPN was 30% (95% confidence interval, CI 25–34%). The pooled prevalence of DPN among patients with type 2 diabetes mellitus was higher than patients with type 1 diabetes mellitus (31.5%, 95% CI 24.4–38.6% vs 17.5%, 95% CI 4.8–30.2%). The pooled prevalence of DPN of studies involving a mixed type of diabetes mellitus was 24.8% (95% CI 13.1–36.5%, I2 = 99.1%).ConclusionsMedical staff should strengthen the evaluation and diagnosis of DPN. Moreover, they need to teach diabetic patients how to prevent this complication.
Keywords:Diabetes mellitus  Diabetic peripheral neuropathy  Prevalence  Meta-analysis
本文献已被 ScienceDirect 等数据库收录!
设为首页 | 免责声明 | 关于勤云 | 加入收藏

Copyright©北京勤云科技发展有限公司  京ICP备09084417号