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Longitudinal multi-modal muscle-based biomarker assessment in motor neuron disease
Authors:Jenkins  Thomas M.  Alix  James J. P.  Fingret  Jacob  Esmail  Taniya  Hoggard  Nigel  Baster  Kathleen  McDermott  Christopher J.  Wilkinson  Iain D.  Shaw  Pamela J.
Affiliation:1.Sheffield Institute for Translational Neuroscience, University of Sheffield, 385a Glossop Road, Sheffield, S10 2HQ, UK
;2.Department of Neurology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK
;3.Departments of Neurophysiology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK
;4.Academic Unit of Radiology, University of Sheffield, Sheffield, UK
;5.Statistics Services Unit, School of Mathematics and Statistics, University of Sheffield, Sheffield, UK
;
Abstract:
Journal of Neurology - Clinical phenotypic heterogeneity represents a major barrier to trials in motor neuron disease (MND) and objective surrogate outcome measures are required, especially for...
Keywords:
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