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Downregulation of betaine homocysteine methyltransferase (BHMT) in hepatocellular carcinoma associates with poor prognosis |
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| Authors: | Jin Bin Gong Zhiwei Yang Nongguo Huang Zhaoquan Zeng Sien Chen Hui Hu Sanyuan Pan Guangdong |
| Institution: | 1.Department of General Surgery, Qilu Hospital of Shandong University, Jinan, 250012, China ;2.Department of General Surgery, The Qingzhou City People’s hospital, Qingzhou, 262500, China ;3.Department of General Surgery, The people’s Hospital of LingCheng, Dezhou, 253500, China ;4.Department of Pathology, Affiliated hospital of Guilin Medical University, Guilin, 541001, Guangxi, China ;5.Laboratory of Liver Injury and Repair Molecular Medicine, Guilin Medical University, Guilin, 541001, Guangxi, China ;6.Department of Hepatobiliary Surgery, The people’s hospital of Liuzhou, Liuzhou, 545001, Guangxi, China ; |
| Abstract: | Tumor Biology - Betaine homocysteine methyltransferase (BHMT) catalyzes the synthesis of methionine using betaine and homocysteine (Hcy), which is restricted to the liver and kidney. Impaired BHMT... |
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