Sarcomatous change in granulosa cell tumor |
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| Authors: | B J Susil E Sumithran |
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| Affiliation: | 1. Department of Pathology, Division of Anatomic Pathology, Penn State Health Milton S. Hershey Medical Center, Hershey, PA, United States;2. Penn State College of Medicine, Hershey, PA, United States;3. Department of Radiology, Division of Breast Imaging, Penn State Health Milton S. Hershey Medical Center, Hershey, PA, United States;4. Department of Pathology, Duke University, Durham, NC, United States;5. Department of Surgery, Penn State Health Milton S. Hershey Medical Center, Hershey, PA, United States |
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| Abstract: | ![]()
Granulosa cell tumors have a tendency for indolent growth and late recurrence. The present case of granulosa cell tumor in a 67-year-old woman is the first, to the authors' knowledge, to be reported as showing sarcomatous transformation with a rapid fatal course. Both the granulosa cell and fibrothecomatous elements appear to have undergone sarcomatous change with some evidence to suggest rhabdomyosarcomatous differentiation. The sarcomatous component was present in metastatic deposits. |
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