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| HIV合并HPV阳性标本中HPV的型别检测 | |
| 引用本文： | 温贵华,刘晋洪,黄玲,李海,郭夏娜,翁琼琳,何春承. HIV合并HPV阳性标本中HPV的型别检测[J]. 热带医学杂志, 2009, 9(8) |
| 作者姓名： | 温贵华 刘晋洪 黄玲 李海 郭夏娜 翁琼琳 何春承 |
| 作者单位： | 深圳市宝安区慢性病防治院,深圳,518133 |
| 基金项目： | 深圳市科技计划项目(医疗卫生类) |
| 摘 要： | 目的探讨深圳地区人类免疫缺陷病毒(HIV)阳性人群中人乳头瘤病毒(HPV)感染分型情况,为HIV阳性人群中HPV感染的防治提供依据。方法运用荧光PCR方法和反向斑点杂交技术对HPV阳性患者进行HPV分型检测。结果在HIV感染者中,利用反向点杂交分型方法对40例HPV阳性标本进行HPV基因分型。其中单型感染有18例(45.0%),混合感染有19例(47.5%),共检出16种HPV型别,其中包括11种高危型(16、18、31、33、35、45、52、56、58、68、73型)和5种低危型(6、11、42、44、54型)。在16种型别中,感染率最高的为16型(25.0%),其次为52型(17.5%)、58型(15.0%)。结论感染HIV人群中生殖器部位HPV的感染率较高,在HIV阳性人群中检出性病相关的高危HPV 16/52/58亚型,对HIV阳性人群中HPV感染的防治有重要指导意义。 |
| 关 键 词： | HIV HPV PCR HPV分型 |
Typing of HPV in Patients with Both HIV and HPV Infection |
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| WEN Gui-hua,LIU Jin-hong,HUANG Ling,LI Hai,GUO Xia-na,WENG Qiang-lin,HE Chun-cheng. Typing of HPV in Patients with Both HIV and HPV Infection[J]. Journal Of Tropical Medicine, 2009, 9(8) | |
| Authors: | WEN Gui-hua LIU Jin-hong HUANG Ling LI Hai GUO Xia-na WENG Qiang-lin HE Chun-cheng |
| Affiliation: | Baoan District Chronic Disease Control Hospital of Shenzhen City;Shenzhen 518133;China |
| Abstract: | Objective To study the situation of HPV infection among the HIV positive subjects in the Shenzhen area and to provide the basis for the prevention and cure of HPV infection.Method Fluorescence PCR and reverse spot hybridization were used for HPV typing.Result 40 cases of HPV positive samples were analyzed.18 cases(45%)had the infection by a single type of HPV.19 cases(47.5%)had mixed infection,in which 16 HPV types were identified.These included 11 high risk types(type16,18,31,33,35,45,52,56,58,68,73)and 5 ... |
| Keywords: | HIV HPV PCR HPV type |
| 本文献已被 CNKI 万方数据 等数据库收录！ | |