| ~(25)Ⅰ标记人血白蛋白在家兔体内生物半减期的测定 |
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| 引用本文： | 黄松林,焦丽华.~(25)Ⅰ标记人血白蛋白在家兔体内生物半减期的测定[J].中国输血杂志,1990,3(3):120-122. |
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| 作者姓名： | 黄松林 焦丽华 |
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| 摘 要： | 本文报道用~(125)I 标记的两种工艺生产的人血白蛋白制品,在两组家兔体内进行生物半减期的对比实验,通过测定和直线对数方程计算,两种白蛋白在家兔体内的生物半减期分别为69±26小时和85±15小时,标记人血白蛋白在两组家兔体内存留时间均在10天以上。结果表明,两种工艺生产的人血白蛋白制品其内在质量和稳定性是一致的。
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| 关 键 词： | 清蛋白 兔 生物半减期 |
Determination of Biological Half-Life of ~(125)(?)-labelled Human Serum Albumin in Rabbits |
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| Abstract: | A comparative experiment with the biological half-life of ~(125)I-labe- lled human serum albumin prepara- tions,produced by two kinds of te- chnological process,was performed in rabbits.The biological half-life of two human serum albumin prepa- rations in rabbits,obtained from de- termination and linear logarithmic equation calculation,was 69±26 hours and 85±15 hours respectively. The survival time of every labelled human serum albumin preparation in two groups of rabbits was above 10 days.Result of the experiment show- ed that the intrinsic quality and stability of the human serum albumin serum albumin preparation,produced by the two different technological processes,were in agreement. |
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