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延胡索生物碱化学成分及其抗肿瘤作用的研究进展
引用本文:万莉,钱晓萍,刘宝瑞. 延胡索生物碱化学成分及其抗肿瘤作用的研究进展[J]. 陕西肿瘤医学, 2012, 0(5): 1042-1044
作者姓名:万莉  钱晓萍  刘宝瑞
作者单位:[1]南京中医药大学附属中西医结合鼓楼临床医学院肿瘤中心,江苏南京210008 [2]南京大学医学院附属鼓楼医院肿瘤中心, 江苏南京210008
基金项目:南京市卫生局重点项目(编号:ZKX09017)
摘    要:
延胡索在临床治疗中运用广泛,其主要成分为生物碱。现代研究表明延胡索生物碱中的延胡索碱、延胡索乙素、小檗碱、黄连碱巴马仃、d-海罂粟碱、d-异波尔定等成分具有一定的抗肿瘤作用。本文就近年来延胡索生物碱的化学成分及其抗肿瘤作用研究的进展情况作一综述。

关 键 词:延胡索生物碱  化学成分  抗肿瘤作用

Progress of research on the chemical constituents and anti-tumor activity of alkaloid fraction of Corydalis
WAN Li,QIAN Xiaoping,LIU Baorui. Progress of research on the chemical constituents and anti-tumor activity of alkaloid fraction of Corydalis[J]. Shaanxi Oncology Medicine, 2012, 0(5): 1042-1044
Authors:WAN Li  QIAN Xiaoping  LIU Baorui
Affiliation:1Department of Oncology,Drum Tower Clinical Hospital Affiliated to Nanjing University of Traditional Chinese Medicine and Clinical Cancer Institute of Nanjing University,Nanjing 210008,China;2Nanjing Drum Tower Hospital,The Affiliated Hospital of Nanjing University Medical School,Nanjing 210008,China.
Abstract:
Corydalis yanhusuo,the main chemical constituents of which are alkaloids,is widely used in the clinical treatment.Modern researches have showed that some constituents of the alkaloid fraction of Corydalis have antitumor activity,such as berberine,palmatine,glaucine,and boldine.The artical submitted the new progress of study in the chemical constituents and the anti-tumor activity of the alkaloid fraction of Corydalis yanhusuo.
Keywords:alkaloid fraction of Corydalis  chemical constituents  anti-tumor effects
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