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A case study of advanced gastric cancer patient treated with S-1+paclitaxel/lentinan
Authors:Nakai Koji  Yamada Masanori  Ueyama Yosuke  Ozaki Takashi  Michiura Taku  Inoue Kentaro  Kawaguchi Yusai  Takada Hideho  Nakane Yasushi  Kwon A-Hon
Affiliation:Department of Surgery, Kansai Medical University.
Abstract:A 47 -year-old male presented with gastric cancer, with right cervical and para-aortic lymph node metastases. The patient had not undergone a curative operation, but was treated with immunochemotherapy in combination with S-1 60 mg/m2(2 weeks administration and 2 weeks rest), paclitaxel 60 mg/m2(day 1, 8, 15), and Lentinan 2mg/body(day 1, 8, 15). After 3 courses of this treatment, no hot-spots were identified on cervical and para-aorta lymph nodes by PET-CT examination. We decided to perform total gastrectomy with D3 lymphadenectomy and Roux-en Y reconstruction. On histopathological examination, no malignancy was seen in the lymph nodes and the main tumor was judged to be grade 2. With this combined immunochemotherapy, the patient had a favorable outcome without side effects, which proved effective for far advanced gastric cancer.
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