| 桂枝附子去桂加白术汤对佐剂性关节炎大鼠的血清肿瘤坏死因子水平的影响 |
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| 引用本文： | 杜力,谷松. 桂枝附子去桂加白术汤对佐剂性关节炎大鼠的血清肿瘤坏死因子水平的影响[J]. 实用中医内科杂志, 2011, 25(5): 40-41. DOI: 10.3969/j.issn.1671-7813.2011.05.19 |
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| 作者姓名： | 杜力 谷松 |
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| 作者单位： | 辽宁中医药大学,辽宁沈阳,110032 |
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| 摘 要： | [目的]通过检测肿瘤坏死因子在佐剂性关节炎大鼠模型的水平,探讨桂枝附子去桂加白术汤治疗佐剂性关节炎大鼠的作用机制。[方法]用弗氏完全佐剂诱导大鼠佐剂性关节炎,采用ELISA方法检测肿瘤坏死因子水平的变化。[结果]桂枝附子去桂加白术汤组肿瘤坏死因子水平较模型组明显降低(P<0.05)。[结论]桂枝附子去桂加白术汤能有效抑制大鼠体内肿瘤坏死因子水平,对类风湿性关节炎有治疗作用。
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| 关 键 词： | 佐剂性关节炎 肿瘤坏死因子 桂枝附子去桂加白术汤 |
Guizhi Fuzi Quguijiabaizhu Tang on Adjuvant Arthritis in Rats Serum Levels of Tumor Necrosis Factor |
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| DU Li,GU Song. Guizhi Fuzi Quguijiabaizhu Tang on Adjuvant Arthritis in Rats Serum Levels of Tumor Necrosis Factor[J]. , 2011, 25(5): 40-41. DOI: 10.3969/j.issn.1671-7813.2011.05.19 |
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| Authors: | DU Li GU Song |
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| Affiliation: | DU Li,GU Song(Liaoning University of TCM,Shenyang 110032,Liaoning,China) |
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| Abstract: | [Objective]Through testing the TNF-α in adjuvant arthritis(AA) rats model expression,Explore a to AA rats treatment function and its mechanism.[Methods]The rats were given complete Freund’ s adjuvant to induce adjuvant arthritis.Adopt ELISA method to detection the level of TNF-α change.[Results]Compare guizhi fuzi quguijiabaizhu tang group to model group,The level of TNF-α obviously reduced(P<0.05).[Conclusion]Guizhi fuzi qugui jiabaizhu tang can effectively restrain the rats’TNF-α content,rheumatoid arthritis have therapeutic effect. |
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| Keywords: | rheumatoid arthritis TNF-α guizhi fuzi quguijiabaizhu tang |
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