| 多发性硬化症与可溶性白细胞介素-2受体的关系 |
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| 引用本文： | 刘举珍,李润今. 多发性硬化症与可溶性白细胞介素-2受体的关系[J]. 实用临床医学(江西), 2011, 12(3): 1-2,5 |
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| 作者姓名： | 刘举珍 李润今 |
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| 作者单位： | 刘举珍,LIU Ju-zhen(内蒙古自治区人民医院,核医学科,呼和浩特,010017);李润今,LI Run-jin(内蒙古自治区人民医院神经内科,呼和浩特,010017) |
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| 摘 要： | 目的 探讨多发性硬化症(multiple sclerosis,MS)患者血清中可溶性白细胞介素2受体(sIL-2R)水平的变化及临床意义.方法 将21例 MS患者按病情分为2组,MS急性复发组(n=15例)和MS缓解组(6例).另选健康体检者(n=25)为对照组.采用双抗体夹心ELISA法检测3组血清sIL-2R水平的变化.结果 MS急性复发组和MS缓解组血清中sIL-2R水平均显著高于对照组(均P< 0.01);MS急性复发组sIL-2R 水平高于MS缓解组(P<0.05).重型MS急性复发者SIL-2R水平高于轻型MS急性复发者(P＜0.05).结论 检测sIL-2R 水平的变化可用于评估机体免疫状态和作为MS 患者病情严重程度的标志.
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| 关 键 词： | 多发性硬化 受体 可溶性白细胞介素2 复发 缓解 |
Relation of Soluble Interleukin-2 Receptor in Patients with Multiple Sclerosis |
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| LIU Ju-zhen,LI Run-jin. Relation of Soluble Interleukin-2 Receptor in Patients with Multiple Sclerosis[J]. Practical Clinical Medicine, 2011, 12(3): 1-2,5 |
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| Authors: | LIU Ju-zhen LI Run-jin |
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| Affiliation: | LIU Ju-zhena,LI Run-jinb(a.Department of Nuclear Medicine,b.Department of Neurology,Inner Mongolia Autonomous Region People's Hospital,Hohhot 010017,China) |
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| Abstract: | Objective To explore the changes in serum soluble interleukin 2 receptor(sIL-2R) levels and the clinical significance in multiple sclerosis(MS) patients.Methods Twenty-one MS patients were divided into two groups:MS acute relapse group(15 cases) and MS remission group(6 cases).Furthermore,25 healthy control subjects were recruited.Serum sIL-2R levels were measured using a double antibody sandwich ELISA.Results Serum sIL-2R levels in MS acute relapse group and MS remission group were significantly higher tha... |
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| Keywords: | multiple sclerosis receptor soluble interleukin 2 relapse remission |
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