新生儿高胆红素血症110例病因分析

目的:探讨新生儿高胆红素血症的防治方法.方法:对2007年10月～2008年12月在我科住院的110例患有高胆红素血症的新生儿进行病因分析.结果:110例病例中,由围生期因素所致64例,占58.18%,这些因素主要包括窒息、剖宫产、胎膜早破、宫内窘迫、羊水粪染、早产、高龄初产、产妇患妊娠胆瘀及产前使用催产素、镇静药等;新生儿自身疾病所致26例,占23.64%,主要包括感染、溶血、畸形等.其中感染16例,占总数的14.55%;母乳性黄疸14例,占12.73%;原因不明6例,占5.45%.结论:围生期因素是导致新生儿高胆红素血症的主要原因,其次是新生儿自身疾病,尤以感染为主.做好围生期保健,提高产科质量,及时预防控制感染是降低新生儿高胆红素血症发生率的关键.

Causes analysis of neonatal hyperbilirubinemia in 110 cases

Objective：To study the diagnosis and treatment of neonatal hyperbilirubinemia.Methods：110 hospitalized cases of neonatal hyperbilirubinemia from October 2007 to December 2008 in our hospital were analyzed for causes.Results：Among 110 cases,64 cases were caused by perinatal factors,accounting for 58.18% ,which included asphyxia,cesarean section,premature rupture of membrane,fetal distress,meconium-stained amniotic fluid,premature birth, elderly primipara,pregnant cholestasis,antenatal oxitocin and sedatives,etc.26 cases were caused by neonatal diseases,accounting for 23.64%,which mainly included infection, hemolysis, malforma-tions,etc.Among them, there were 16 cases of infection （14.55%）,14 cases of breast milk jaundice （12.73%）,6 cases of unknown cause （5.45%）.Conclusion：The perinatal factors are the main reason to neonatal hyperbilirubinemia, followed by the neonatal diseases,especially infection.Good perinatal care,improving the obstetric quality and timely preventing and controlling infection are the keys to reduce the incidence of neonatal hyperbilirubinemia.