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Primary leiomyosarcoma of the thyroid gland
Authors:Osamu Ozaki  Kiminori Sugino  Takashi Mimura  Kunihiko Ito  Seiichi Tamai  Yasuhiro Hosoda
Affiliation:(1) Department of Surgery, Ito Hospital, 4-3-6 Jingumae, Shibuya-ku, 150 Tokyo, Japan;(2) Department of Pathology, National Defense Medical College, 3-2 Namiki, 359 Tokorozawa, Japan;(3) Department of Pathology, Keio University School of Medicine, 35 Shinanomachi, Shinjuku-ku, 160 Tokyo, Japan
Abstract:Primary leiomyosarcoma of the thyroid gland is extremely rare, and to the best of our knowledge only five well-documented cases have been reported in the world literature. We herein report a 58-year-old female patient with primary leiomyosarcoma of the thyroid who was successfully treated by total thyroidectomy with a modified neck dissection. Immunohistochemically, the tumor cells showed positive reactivity to α-smooth muscle actin and vimentin. Radical surgery was thus considered to be essential in the treatment of this rare but rather aggressive malignancy.
Keywords:leiomyosarcoma  thyroid gland  α  -smooth muscle actin
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