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喉癌组织中VEGF-D表达与淋巴管生成及预后的关系
引用本文:王莹,李文媛,贾桦,佟晓杰. 喉癌组织中VEGF-D表达与淋巴管生成及预后的关系[J]. 解剖科学进展, 2011, 17(2): 116-120
作者姓名:王莹  李文媛  贾桦  佟晓杰
作者单位:1. 牡丹江医学院解剖教研室,黑龙江,牡丹江157011
2. 中国医科大学解剖教研室,辽宁,沈阳,110001
基金项目:黑龙江省普通高等学校青年学术骨干支持计划项目
摘    要:
目的 探讨血管内皮生长因子-D(Vessel endothelium growth factor D,VEGF-D)在喉癌组织中的表达规律及与淋巴管密度(LVD)和淋巴转移之间的关系及其在喉癌预后中的意义.方法 以45例经病理确诊的喉癌组织为实验组,以20例喉良性病变组织为对照组,采用免疫组化SP法对上述组织中VEGF...

关 键 词:血管内皮生长因子-D  人喉肿瘤  淋巴管生成  预后

The relationship between vascular endothelial growth factor D expression and lymphangiogenesis as well as prognosis in human laryngeal carcinoma
WANG Ying,LI Wen-yuan,JIA Hua,TONG Xiao-jie. The relationship between vascular endothelial growth factor D expression and lymphangiogenesis as well as prognosis in human laryngeal carcinoma[J]. Progress of Anatomical Sciences, 2011, 17(2): 116-120
Authors:WANG Ying  LI Wen-yuan  JIA Hua  TONG Xiao-jie
Affiliation:WANG Ying1,LI Wen-yuan1,JIA Hua2,TONG Xiao-jie2(1.Department of Anatomy,Mudanjiang Medical College,Heilongjiang Mudanjiang 157011,2. Department of Anatomy,China Medical University,Liaoning Shenyang 110001 China)
Abstract:
Objective To investigate the expression of vascular endothelial growth factor D(VEGF-D) in human laryngeal cancer to explore the relationship of the expression with lymphangiogenesis,lymph node metastasis and their prognosis significance. Methods Forty five specimens of human laryngeal cancer and twenty benign laryngeal tissues were used to observe the expression of VEGF-D by immunohistochemistry S-P method. The lymphatic vessels density(LVD) was evaluated by 5'-Nucleotides-alkaline phosphates double staini...
Keywords:vessel endothelium growth factor D  human laryngeal cancer  lymphangiogenesis  prognosis  
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