浸润性膀胱癌术前超选择性动脉化疗的临床观察

目的 探讨浸润性膀胱癌术前动脉化疗的临床疗效。方法 对１４例保留膀胱手术患者在术前采用超选择性髂内动脉化疗栓塞术治疗。结果 动脉化疗后２～３周,妇现肿瘤缩小２０％～５０％,术中见肿瘤及周围组织有散在陈旧性出血与小血管内血栓形成;手术出血少。病理检查光镜下见癌大片状坏死、退变及炎性等改变。随访５～２４个月,平均１９．６个月。１例Ｔ３Ｎ１Ｍ０复发为Ｔ１Ｎ０Ｍ０,其余未复发。结论 髂内动脉化疗操作简单安

Preoperative superselective intra-internal iliac arterial chemotherapy for invasive bladder cancer and curative analysis

Objective To study clinical effects of preoperative intra internal iliac arterial chemotherapy for invasive bladder cancer. Methods 14 cases of invasive bladder cancer underwent superselective intra internal iliac arterial chemotherapy before consevative cystectomy. Results After 2 3 week therapy, reduction of cancer volume (20% 50%), clotted by thrombus in the blood vessels of the cancer or circumferential tissue, and decreased bleeding were found. Pathomorphological features incloded large palchy necrosis, degeneration, and inflammatory changes of carcinoma tissue. Follow up ranged from 5 to 42 months (mean 19.6 months). One (T 3 N 1 M 0) of the cases (0 7%) relapsed into T 1N OM O and the others did not. Conclusions The intra internal iliac arterial method, simple, safe, coordinates in preoperation for invasive bladder cancer, and increases the operative opportunity for preservation of functional bladder.