原发性256例软组织肉瘤手术治疗的临床分析

目的：探讨软组织肉瘤的诊断、手术治疗方法及其疗效。方法：对256例原发性软组织肉瘤患者的治疗情况进行回顾性分析。行局部广泛切除及根治切除术,对侵犯骨组织的软组织肉瘤则按微波原位灭活保肢手术处理。切除肿瘤后,行血管修复重建、带血管蒂游离皮瓣转移、局部皮瓣转移、肌腱移位、肌皮瓣移位。结果：发病年龄为20-70岁,占62.11%（159/256）,常见的病理类型为滑膜肉瘤、恶性纤维组织细胞瘤、脂肪肉瘤、横纹肌肉瘤、纤维肉瘤,占65.23%（167/256）。Kaplan-Meier法计算5年生存率为63.28%。结论：诊断采用CT、MRI为主的影像学,治疗以手术为主,辅助放疗和化疗。

Clinical analysis of 256 cases of soft tissue sarcomas with surgery treatment

Objective： To explore the diagnosis,surgery treatment and therapeutic effect of soft tissue sarcomas.Methods：Surgical therapies of 256 primary soft tissue sarcoma cases were reviewed retrospectively.These therapies included local resection,radical resection and limb salvage surgery with microwave.After the resections,many adjunctive surgeries were performed to help recovery,such as vascular reconstruction,pedicled free flap transfer,tendon transfer,musculocutaneous flap transfer,etc.Results：Soft tissue sarcoma often appears at the age of 20 to 70 year old（62.11%）.The common pathology types are synoviosarcoma,malignant fibrohistiocytoma, liposarcoma,rhabdomyosarcoma,and fibrosarcoma.The 1-,3-,5 year tumor-free survival rates were 83.98 %,75.00 %,63.28 %,respectively.Conclusion：CT,MRI and pathology are main diagnosis methods.Operation is the main treatment,combined with radiotherapy and chemotherapy.