Livin、Ki-67蛋白在胃癌中的表达及意义 |
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引用本文: | 李梅,姚乐,惠起源. Livin、Ki-67蛋白在胃癌中的表达及意义[J]. 陕西肿瘤医学, 2011, 0(2): 302-304 |
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作者姓名: | 李梅 姚乐 惠起源 |
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作者单位: | [1]陕西省肿瘤医院,陕西西安710061 [2]榆林市第一医院,陕西榆林719000 [3]延安大学附属医院,陕西延安716000 |
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摘 要: | 目的:通过检测胃癌组织中Livin、Ki-67表达与其临床病理指标的关系,探讨两者表达的相关性芨在癌变发生发展中的意义。方法:采用免疫组织化学方法测定Livin、Ki-67在40例胃癌中的表达,分析与胃癌临床病理指标的关系。结果:Livin和Ki-67与淋巴结转移、分化程度有统计学关联(P〈0.05);与性别、年龄、不同浸润深度、不同临床分期间无关(P〉0.05)。Livin、Ki-67在胃癌组织中的表达无关联(P〉0.05)。结论:Livin、Ki-67可能有助于判断胃癌的恶性程度及进展情况,对于胃癌手术的根治和术后化疗有一定指导意义。
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关 键 词: | 胃癌 Livin Ki-67 免疫组化 |
Expression of Livin and Ki- 67 in gastric cancer and significance |
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Affiliation: | LI mei, YAO Le, HUI Qi - yuan(1. Department of Radiotherapy , Shaanxi Tumor Hospital, Xi' an 710061, China ; 2Department of Radiation Oncology, the First People of Yulin , Yulin 719000 , China ; 3 Medical College of Yah' an University, Yan' an 716000, China.) |
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Abstract: | Objective:To study the Livin, Ki -67 expression in gastric cancer in and its clinical significance. Methods: To determine Livin, Ki -67 in 40 cases of gastric cancer by immunohistochemistry. Results: Livin and Ki - 67 were related to lymph node metastasis, ( P 〈 0.05 ) ; on relation with gender, age, depth of invasion, clinical stages (P 〉 0.05 ). Livin, Ki - 67 expression in gastric cancer was not related ( P 〉 0.05). Conclusion: Livin, Ki - 67 may help determine the degree of malignancy of gastric cancer and the progress of gastric cancer. |
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Keywords: | gastric carcinom livin ki - 67 immunohistochemistry |
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