|
|||||
|
|
| 糖尿病患者检测甲状腺激素的临床意义探讨 | |
| 引用本文： | 杨雪,田甜,许安春,王艳,马韬,唐欧,毕冬明. 糖尿病患者检测甲状腺激素的临床意义探讨[J]. 检验医学与临床, 2011, 8(20): 2455-2457. DOI: 10.3969/j.issn.1672-9455.2011.20.012 |
| 作者姓名： | 杨雪 田甜 许安春 王艳 马韬 唐欧 毕冬明 |
| 作者单位： | 1. 成都中医药大学附属医院检验科,610072 2. 四川省成都市第七人民医院检验科,610041 3. 成都中医药大学附属医院核医学科,610072 |
| 摘 要： | 目的探讨甲状腺激素与糖尿病类型、病情及病程的关系。方法选择糖尿病患者197例和健康体检者40例,采用电化学发光法测定血清甲状腺激素三碘甲状腺原氨酸(T3)、总甲状腺素(T4)、游离三碘甲状腺原氨酸(FT3)、游离甲状腺素(FT4)、促甲状腺激素(TSH)水平,采用放射免疫法测定甲状腺激素rT3含量,观察糖尿病不同类型、病情、病程分组中T3、T4、FT3、FT4,TSHr、T3含量变化特点。结果 1型和2型糖尿病组T3、FT3、FT4均显著低于健康对照组(P<0.01),rT3均显著高于健康对照组(P<0.01);1型糖尿病组T3、FT3、FT4低于2型糖尿病组(P<0.05),而rT3高于2型糖尿病组(P>0.05)。7%≤糖化血红蛋白(HbA1c)<10%、10%≤HbA1c<13%、HbA1c≥13%3组的T3、FT3和TSH低于HbA1c<7%组(P<0.05或P<0.01)。随着病程延长,T3、FT3呈降低趋势(P<0.05或P<0.01),rT3呈现升高趋势(P<0.05或P<0.01)。结论甲状腺激素水平对糖尿病患者糖代谢的评估、病情估计及预后判断有重要的临床意义。 |
| 关 键 词： | 糖尿病 甲状腺激素 糖化血红蛋白 |
Study of the clinical significance of the determination of serum thyroid hormones levels in diabetes mellitus patients |
|
| YANG Xue,TIAN Tian,XU An-chun,WANG Yan,MA Tao,TANG Ou,BI Dong-ming. Study of the clinical significance of the determination of serum thyroid hormones levels in diabetes mellitus patients[J]. Laboratory Medicine and Clinic, 2011, 8(20): 2455-2457. DOI: 10.3969/j.issn.1672-9455.2011.20.012 | |
| Authors: | YANG Xue TIAN Tian XU An-chun WANG Yan MA Tao TANG Ou BI Dong-ming |
| Affiliation: | 1.Department of Clinical Laboratory,Affiliated Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610072,China;2.Department of Clinical Laboratory,The Seventh People′s Hospital of Chengdu 610041,China;3.Department of Nuclear Medicine,Affiliated Hospital of Chengdu University of Traditional Chinese Medicine,Chengdu 610072,China) |
| Abstract: | Objective To explore the relationship between thyroid hormone type,state and course of diseases of diabetes mellitus(DM).Methods 197 samples of DM and 40 samples of normal controls were selected.Serum thyroid hormones T3,T4,FT3,FT4 and TSH levels were measured with electrochemiluminescence(ECL).Serum thyroid hormones rT3 levels were measured with Radio Immunoassay(RIA).Then the variational traits of thyroid hormones T3,T4,FT3,FT4,TSH and rT3 were observed in different groups according to the type,state,and ... |
| Keywords: | diabetes mellitus thyroid hormone hemoglobin A1c |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |