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肝硬化患者血清TSGF和GA199联检的临床意义
引用本文:王经鹏. 肝硬化患者血清TSGF和GA199联检的临床意义[J]. 放射免疫学杂志, 2005, 18(6): 463-465
作者姓名:王经鹏
作者单位:山东中医药大学第二附属医院 250000
摘    要:
目的:探讨了肝硬化患者血清TSGF和CA199水平的变化及临床意义。方法:应用放射免疫分析测定51例肝硬化患者血清CA199含量,光电比色法测定TSGF含量,并与35名正常健康人作比较。结果:肝硬化患者血清TSGF和CA199含量均非常显著地高于正常人组(P<0.01),且与血清中AFP含量呈明显的正相关。结论:测定肝硬化患者血清中TSGF和CA199含量对临床诊断和治疗均具有重要的临床价值。

关 键 词:肝硬化  恶性肿瘤特异性生长因子  糖类抗原199
收稿时间:2005-10-14
修稿时间:2005-10-14

Clinical Significance of Combined Determination of Serum TSGF and CA199 Levels in Patients with Hepatic Cirrhosis
Wang Jingpeng. Clinical Significance of Combined Determination of Serum TSGF and CA199 Levels in Patients with Hepatic Cirrhosis[J]. Journal of Radioimmanology, 2005, 18(6): 463-465
Authors:Wang Jingpeng
Abstract:
Objective To study the significance of changes of serum TSGF and CA199 levels in patients with hepatic cirrhosis.Methods Serum CA199 levels(with RIA) and TSGF levels(with biochemical method) were determined in 51 patients with hepatic cirrhosis and 35 controls.Results Serum TSGF and CA199 levels in the patients were significantly higher than those in controls(P<0.01) and were positive correlated with the AFP levels(P<0.01).Conclusion The higher TSGF/AFP levels in patients with cirrhosis might indicate possible tendency toward malignant changes.
Keywords:hepatic cirrhosis  tumor specific growth factor(TSGF)  carbohydrate antigen-199(CA199)
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