| 强直性脊柱炎的骨化研究进展 |
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| 引用本文： | 万文凯,徐一宏,徐卫东.强直性脊柱炎的骨化研究进展[J].中华关节外科杂志（电子版）,2019,13(3):348-352. |
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| 作者姓名： | 万文凯 徐一宏 徐卫东 |
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| 作者单位： | 1. 200433 上海，海军军医大学附属长海医院骨科（关节外科） |
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| 基金项目： | 国家自然科学基金(81672126，81871751) |
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| 摘 要： | 病理性骨化是强直性脊柱炎最主要的特点之一。目前有很多关于强直性脊柱炎骨化的研究，包括炎症与骨化的关系、骨化信号通路及Wnt信号通路等。从不同的方面来研究强直性脊柱炎的骨化过程，彻底弄清其骨化的机制，对治疗强直性脊柱炎有着重要的意义。
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| 关 键 词： | 骨生成 炎症 Wnt信号通路 |
Progress in ossification of ankylosing spondylitis |
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| Wenkai Wan,Yihong Xu,Weidong Xu.Progress in ossification of ankylosing spondylitis[J].Chinese Journal of Joint Surgery(Electronic Version),2019,13(3):348-352. |
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| Authors: | Wenkai Wan Yihong Xu Weidong Xu |
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| Institution: | 1. Department of Joint & Bone Surgery, Changhai Hospital, the First Affiliated Hospital of the Second Military Medical University, Shanghai 200433, China |
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| Abstract: | Pathological ossification is one of the most important features of ankylosing spondylitis. There are many studies on the ossification of ankylosing spondylitis, including the relationship between inflammation and ossification, ossification signal pathway and Wnt signaling pathway. To study the ossification process of ankylosing spondylitis from different aspects and thoroughly understand the mechanism of ossification, it is of great significance for the treatment of ankylosing spondylitis. |
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| Keywords: | Osteogenesis Inflammation Wnt signaling pathway |
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