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| 左旋卡尼汀对缺血心肌能量代谢和心功能的影响 | |
| 引用本文： | 张丽,高春霖. 左旋卡尼汀对缺血心肌能量代谢和心功能的影响[J]. 医学综述, 2008, 14(5): 755-757 |
| 作者姓名： | 张丽 高春霖 |
| 作者单位： | 天津医科大学第二医院麻醉科,天津,300211 |
| 摘 要： | 左旋卡尼汀,又称肉碱,由哺乳动物体内自身合成。左旋卡尼汀的作用是协助长链脂酰辅酶A进入线粒体内膜,进行脂肪酸β-氧化提供能量,加速三磷酸腺苷(ATP)的产生,提高心肌细胞内ATP水平。许多研究表明,左旋卡尼汀可以改善缺血心肌的功能和促进能量代谢。 |
| 关 键 词： | 左旋卡尼汀 缺血心肌 缺血再灌注损伤 能量代谢 |
| 文章编号： | 1006-2084（2008）05-0755-03 |
| 收稿时间： | 2007-07-13 |
| 修稿时间： | 2007-12-04 |
The Effects of L-Carnitine to the Energy Metabolism of Ischemical Reperfusion Myocardium |
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| ZHANG Li,GAO Chun-lin. The Effects of L-Carnitine to the Energy Metabolism of Ischemical Reperfusion Myocardium[J]. Medical Recapitulate, 2008, 14(5): 755-757 | |
| Authors: | ZHANG Li GAO Chun-lin |
| Affiliation: | ZHANG Li,GAO Chun-lin.(Department of Anesthesiology of Second Hospital,Tianjin Medical University,Tianjin 300211,China) |
| Abstract: | L-camitine, also called novain, is synthezised by mammal themselves. It helps long-chain acyl-CoA enter into mitochondrial inner membrane, supply energy for fatty acid carrying out β-oxiation and increasing the levels of the adenosine triphosphate in myocardial cell. Many researches showed that L-camiline can improve functions and energy metabolism of the ischemia myocardium. |
| Keywords: | L-camitine Ischemical myocardium Ischemical reperfusion injury Energy metabolism |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ | |