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口服结肠靶向给药系统的研究进展
引用本文:张林,刘秀菊,翟光喜. 口服结肠靶向给药系统的研究进展[J]. 中国新药与临床杂志, 2011, 0(8)
作者姓名:张林  刘秀菊  翟光喜
作者单位:山东大学药学院;山东省立医院西院药剂科;
基金项目:国家自然科学基金(30973646)
摘    要:口服结肠靶向给药系统在药物转运和治疗结肠局部疾病方面具有重要作用。本文总结了口服结肠靶向给药系统近年来的研究概况,并对结肠靶向药物制剂的体内、外评价方法作一介绍。

关 键 词:口服结肠靶向给药系统  体外研究  评价研究  结肠疾病

Progress on oral colon-specific drug delivery system
ZHANG Lin,LIU Xiu-ju,ZHAI Guang-xi,Ji-nan SH,ONG ,China). Progress on oral colon-specific drug delivery system[J]. Chinese Journal of New Drugs and Clinical Remedies, 2011, 0(8)
Authors:ZHANG Lin  LIU Xiu-ju  ZHAI Guang-xi  Ji-nan SH  ONG   China)
Affiliation:ZHANG Lin1,LIU Xiu-ju2,ZHAI Guang-xi1(1.Pharmacy School of Shandong University,Ji-nan SHANDONG 250012,China,2.Department of Pharmacy,Shandong Provincial Hospital(Western Division),Ji-nan SHANDONG 250022,China)
Abstract:Oral colon-specific drug delivery system(OCDDS)has gained increased importance for the delivery of drugs for the treatment of local diseases associated with the colon in recent years.In this article,the recent development of OCDDS was summarized,and in vitro and in vivo evaluation methods were also discussed.
Keywords:oral colon-specific drug deliverg system  in vitro  evaluation studies  colonic diseases  
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