| 加味补阳还五汤对次声暴露下小鼠学习记忆能力的影响 |
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| 引用本文： | 范建中,杨俊峰,陈景藻,谭晓明.加味补阳还五汤对次声暴露下小鼠学习记忆能力的影响[J].中国康复理论与实践,2007,13(1):35-36. |
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| 作者姓名： | 范建中 杨俊峰 陈景藻 谭晓明 |
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| 作者单位： | 1. 南方医科大学南方医院康复医学科,广东广州市,510515
2. 第四军医大学西京医院康复医学科,陕西西安市,710032 |
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| 摘 要： | 目的观察加味补阳还五汤对16Hz(8Hz),130dB次声暴露下小鼠学习记忆能力的影响。方法将学习记忆能力相近的80只BALB/c小鼠分为16Hz组和8Hz组,其中每组再分为空白对照组、次声对照组以及次声加用药组(根据用药剂量的不同又分高、中、低剂量组),处理14d后测试其学习记忆能力的变化。结果次声对照组的学习记忆能力降低(P<0·05),16Hz用药组较次声对照组的逃逸时间明显缩短(P<0·01),8Hz用药组较次声对照组的逃逸时间无显著性差异,各剂量组之间未见显著性差异。结论16Hz(8Hz),130dB次声暴露14d(2h/d)可引起小鼠学习记忆能力的下降。加味补阳还五汤可以提高16Hz次声暴露后小鼠的学习记忆能力。
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| 关 键 词： | 次声 加味补阳还五汤 学习记忆 小鼠 |
| 文章编号： | 1006-9771（2007）01-0035-02 |
| 收稿时间： | 2006-09-07 |
| 修稿时间： | 2006年9月7日 |
Protection by Jiawei Buyang Huanwu Decoction from the Harm of Infrasound (16 Hz,130 dB)in Mice |
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| FAN Jian-zhong, YANG Jun-feng , CHEN Jing-zao ,et al..Protection by Jiawei Buyang Huanwu Decoction from the Harm of Infrasound (16 Hz,130 dB)in Mice[J].Chinese Journal of Rehabilitation Theory and Practice,2007,13(1):35-36. |
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| Authors: | FAN Jian-zhong YANG Jun-feng CHEN Jing-zao |
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| Institution: | Department of Rehabilitation Medicine, Nan fang Hospital , Nanfang Medicine University, Guangzhou 510515, Guangdong, China |
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| Abstract: | ObjectiveTo study the effects of Jiawei Buyang Huanwu Decoction on learning and memory abilities of mice exposed to 130 dB infrasound (16 Hz). Methods80 BALB/c mice were divided into blank-control group, infrasound-control group, infrasound and drug-treated group (it was divided into 3 sub-groups according to dose). Learning and memory abilities were measured 14 d later. ResultsCompared with blank-control group, learning and memory abilities decreased (P<0.05) in infrasound-control group. Compared with infrasound-control group, learning and memory abilities increased(P<0.01) in infrasound and drug-treated group. Conclusion16 Hz,130 dB infrasound could damage learning and memory abilities. Jiawei Buyang Huanwu Decoction could protect mice from learning and memory harm exposed to the infrasound. |
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| Keywords: | infrasound Jiawei Buyang Huanwu Decoction learning and memory mice |
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