Lactoferrin inhibits the inflammatory and angiogenic activation of bovine aortic endothelial cells |
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| Authors: | Mijung Yeom Jongbong Park Bombi Lee Sang-Yun Choi Kyoung Soo Kim Hyejung Lee Dae-Hyun Hahm |
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| Affiliation: | (1) Department of Oriental Medicine, Acupuncture and Meridian Science Research Center, Kyung Hee University, Hoegi-dong, Dongdaemoon-gu, Seoul, 130-702, Republic of Korea;(2) School of Life Science and Biotechnology, Korea University, Seoul, 136-701, Republic of Korea;(3) East-West Bone and Joint Research Institute, East-West Neo Medical Center, Kyung Hee University, 149 Sangil-dong, Gangdong-gu, Seoul, 134-727, Republic of Korea; |
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| Abstract: | Objective Lactoferrin (Lf) is known to have anti-cancer and anti-inflammatory activities; however, its therapeutic mechanism has not been defined. In this study, to explain the therapeutic mechanism of Lf, we examined the effect of Lf on endothelial cell activation, leukocyte integration, and angiogenesis in vitro. |
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