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长毛囊孔菌发酵液化学成分研究
引用本文:高建,李俊,麻兵继,阮元. 长毛囊孔菌发酵液化学成分研究[J]. 安徽医药, 2009, 13(8): 877-878
作者姓名:高建  李俊  麻兵继  阮元
作者单位:安徽医科大学第一附属医院,安徽,合肥,230022;安徽医科大学药学院,安徽,合肥,230032;安徽医科大学药学院,安徽,合肥,230032;河南农业大学农学院中药材系,河南,郑州,450002
摘    要:目的研究长毛囊孔菌(Trametes versatillis. Berk)液体深层发酵产生次生代谢产物。方法利用常规色谱分离技术对长毛囊孔菌发酵液和菌丝体的提取物进行分离。结果分离鉴定了7个化合物,经波谱分析分别鉴定为D-阿洛醇(1)、3β-羟基-麦角甾-5,7,22-三烯(2)、3β-羟基-5α,8α-过氧化麦角甾-6,22-二烯(3)、eburicoic acid(4)、3β-羟基-5α,8α-过氧麦角甾-6,22-二烯(5)、tumulosic acid(6)和软脂酸-α-甘油酯(7)。结论以上化合物都为长毛囊孔菌中首次报道,且三萜化合物在长毛囊孔菌发酵液及发酵菌丝中含量较大,具有一定的深入研究价值。

关 键 词:长毛囊孔菌  菌丝体  三萜  eburicoic acid

Chemical study on the mycelia of Trametes versatillis. Berk
GAO Jian,LI Jun,MA Bing-ji,RUAN Yuan. Chemical study on the mycelia of Trametes versatillis. Berk[J]. Anhui Medical and Pharmaceutical Journal, 2009, 13(8): 877-878
Authors:GAO Jian  LI Jun  MA Bing-ji  RUAN Yuan
Affiliation:1. The First Affiliated Hospital of Anhui Medical University, Anhui Hefei 230022; 2. Dept of Pharmacy ,Anhui Medical University ,Anhui Hefei 230032; 3. Department of traditional Chinese medicine ,Agronomy college of Henan Agriculture university, Zhengzhou 450002 )
Abstract:Aim To investigate the chemical constituents of the mycelia of Trametes versatillis.Berk.Methods Chemical constituents of the mycelia of Trametes versatillis.Berk were isolated by column chromatography.Results Six compounds were isolated and identified as D-allitol(1),3β-hydroxyergosta-5,7,22-triene(2),3β-hydroxy-5α,8α-epidioxyergosta-6,22-diene(3),eburicoic acid(4),3β-hydroxy-5α,8α-epidioxyergosta-6,22-diene(5),tumulosic acid(6) and glycerol monoplmitate(7),respectively.Conclusion All the compounds above were isolated from the Trametes versatillis for the first time. Triterpenes were the main compounds of the mycelia of Trametes versatillis. Berk and have the potential for the further investigation.
Keywords:eburicoic acid
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