Delayed effects of enalapril on structural characteristics of the glomerular apparatus in the kidneys of NISAG rats |
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| Authors: | E. E. Filyushina M. D. Shmerling V. A. Lazarev I. I. Buzueva D. R. Kudryashova A. L. Markel’ G. S. Yakobson |
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| Affiliation: | (1) Institute of Physiology, Siberian Division of the Russian Academy of Medical Sciences, Russia;(2) Institute of Cytology and Genetics, Siberian Division of the Russian Academy of Sciences, Novosibirsk |
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| Abstract: | Structural characteristics of renal glomeruli were studied in adult hypertensive NISAG rats (hereditary stress-induced hypertension) receiving antihypertensive drug enalapril, an inhibitor of angiotensin-converting enzyme, on days 28–58 of life. Treatment with enalapril (25 mg/kg perorally) in the early period of postnatal ontogeny produced delayed hypotensive and nephroprotective effects. __________ Translated from Byulleten’ Eksperimental’noi Biologii i Meditsiny, Vol. 141, No. 2, pp. 124–127, February, 2006 |
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| Keywords: | arterial hypertension kidney enalapril morphometry |
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