| 献血员HBV携带状况的筛检方法研究 |
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| 引用本文： | 肖亦璟,谭红专,汤学民,罗荣.献血员HBV携带状况的筛检方法研究[J].中南大学学报(医学版),1990(4). |
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| 作者姓名： | 肖亦璟 谭红专 汤学民 罗荣 |
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| 作者单位： | 湖南医科大学流行病学教研室，湖南医科大学流行病学教研室，湖南医科大学流行病学教研室，湖南医科大学流行病学教研室 河北省邯郸市卫生防疫站 |
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| 摘 要： | 将应用常规RPHA法检查HBsAg阴性的1074份献血员血清再用ELISA和SPRIA法检测。其中又查出HBsAg、HBeAg和抗-HBc-IgM标志,其阳性率分别达5.96％,2.14％和3.35％,HBV携带率竟高达9.68％。说明用常规RPHA法筛选出的HBsAg阴性献血员仍有传播乙型肝炎的危险。用ELISA法并联检测HBsAg和抗-HBc-IgM,在RPHA法检查HBsAg阴性的献血员中、其阳性率为8.29％,敏感度达85.58％,因而这种并联筛检方法可成为一种切实可行的筛检方法。
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| 关 键 词： | 乙型肝炎 传播 输血 预防和控制 |
METHODS OF SCREENING HBV CARRIERS IN BLOOD DONORS |
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| Xiao Yijing Tan Hongzhuan Tang Xuemin Luo Rong.METHODS OF SCREENING HBV CARRIERS IN BLOOD DONORS[J].Journal of Central South University (Medical Sciences)Journal of Central South University (Medical Sciences),1990(4). |
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| Authors: | Xiao Yijing Tan Hongzhuan Tang Xuemin Luo Rong |
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| Institution: | Xiao Yijing Tan Hongzhuan Tang Xuemin Luo RongDepartment of Epidemiology,Hunan Medical University |
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| Abstract: | Cryopreseved sera of 1074 blood donors that had proved HBsAg negative by RPHA were reexam-ined for HBsAg HBeAg and anti-HBc-IgM by ELISA and SPRIA and donors residue sera after ELISA, with either HBsAg, HBeAg, or anti-HBc-IgM positive had a test for HBV-DNA with spot hybridization. The positive rate of HBsAg, HBeAg, anti-HBc-IgM and HBV-DNA were 5. 96%, 2. 14% , 3. 35% and 5. 40% respectively. As ELISA screen on each marker had sensitivities below 70% ,and parallel of two markers can increase the sensitivity; parallel of HBsAg and anti-HBc-IgM, sensitivity reached up to 85. 58% ,it is rather practicable. The RPHA detection of HBsAg have a very high risk of transmission of HBV,that should be refused. |
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| Keywords: | transmission hepetitis B virus blood transfussion prevention and control 1)Sanitation and anti-epidemic station of Handan city Heber |
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