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| HRG-1基因在膀胱癌和正常膀胱组织中的表达 | |
| 引用本文： | 乔少谊,邵晨,付国庆,张磊,王哲,师长宏,汪涌,苏鹏霄,窦小亮.HRG-1基因在膀胱癌和正常膀胱组织中的表达[J].现代泌尿外科杂志,2011,16(2):145-147. |
| 作者姓名： | 乔少谊 邵晨 付国庆 张磊 王哲 师长宏 汪涌 苏鹏霄 窦小亮 |
| 作者单位： | 1. 第四军医大学,西京医院泌尿外科,陕西西安,710032 2. 第四军医大学,流行病学教研室,陕西西安,710032 3. 第四军医大学,西京医院病理科,陕西西安,710032 4. 第四军医大学,实验动物中心,陕西西安,710032 5. 第四军医大学,唐都医院泌尿外科,陕西西安,710032 |
| 摘 要： | 目的观察HRG-1基因在膀胱正常组织和膀胱癌组织中的表达,探讨HRG-1基因表达与膀胱肿瘤病理分级和临床分期的关系。方法应用免疫组化SP法检测63例膀胱癌和28例膀胱正常组织石蜡标本中HRG-1表达情况,并进行相关临床病理分析。结果在正常膀胱组织和膀胱癌组织中HRG-1表达有显著性差异（P〈0.05）;HRG-1的阳性表达与膀胱癌病例分级、临床分期之间有显著性差异（P〈0.05）。结论 HRG-1基因在膀胱癌组织中表达水平显著提高,提示该基因可能对膀胱肿瘤病理分级和临床分期有一定的指导意义。 |
| 关 键 词： | 膀胱肿瘤 人类血红素敏感基因1 病理分级 临床分期 |
Expression of HRG-1 gene in carcinoma of urinary bladder and normal bladder tissues |
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| QIAO Shao-yi,SHAO Chen,FU Guo-qing,ZHANG Lei,WANG Zhe,SHI Chang-hong,WANG Yong,SU Peng-xiao,DOU Xiao-liang.Expression of HRG-1 gene in carcinoma of urinary bladder and normal bladder tissues[J].Journal of MOdern Urology,2011,16(2):145-147. | |
| Authors: | QIAO Shao-yi SHAO Chen FU Guo-qing ZHANG Lei WANG Zhe SHI Chang-hong WANG Yong SU Peng-xiao DOU Xiao-liang |
| Institution: | QIAO Shao-yi1,SHAO Chen1,FU Guo-qing1,ZHANG Lei2,WANG Zhe3,SHI Chang-hong4,WANG Yong5,SU Peng-xiao1,DOU Xiao-liang1(1.Department of Urology,2.Department of Epidemiology,3.Department of Pathology,4.Department of Experimental Animal Center,Xijing Hospital,5.Department of Urology,Tangdu Hospital,Fourth Miliary Medical University,Xi'an 710032,China) |
| Abstract: | Objective To observe HRG-1 gene expression in carcinoma of urinary bladder and normal urinary bladder tissues,and to explore the relationship between HRG-1 gene expression and bladder tumor pathologic stage and the clinical stages.Methods Immunohistochemisty was used to detect the expression of HRG-1 in 63 cases of bladder cancer and 28 normal bladder tissues.Results HRG-1 gene expression had significant differences between bladder cancer and normal bladder tissues(P<0.05);HRG-1 gene positive expression had... |
| Keywords: | carcinoma of urinary bladder HRG-1 pathological grades clinical stages |
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