The effects of hyperbaric oxygen therapy on oxidative stress,inflammation, and symptoms in children with autism: an open-label pilot study |
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| Authors: | Daniel A Rossignol Lanier W Rossignol S Jill James Stepan Melnyk Elizabeth Mumper |
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| Affiliation: | (1) International Child Development Resource Center, 3800 West Eau Gallie Blvd., Suite 105, 32934 Melbourne, FL, USA;(2) University of Arkansas for Medical Sciences, Department of Pediatrics, Arkansas Children's Hospital Research Institute, 1120 Marshall St., 72202 Little Rock, AR, USA;(3) Advocates for Children, Ltd., 2015 Tate Springs Rd., Lower Level, Suite 2, 24501 Lynchburg, VA, USA;(4) Current address: 2919 Confederate Ave., 24501 Lynchburg, VA, USA |
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| Abstract: | Background Recently, hyperbaric oxygen therapy (HBOT) has increased in popularity as a treatment for autism. Numerous studies document oxidative stress and inflammation in individuals with autism; both of these conditions have demonstrated improvement with HBOT, along with enhancement of neurological function and cognitive performance. In this study, children with autism were treated with HBOT at atmospheric pressures and oxygen concentrations in current use for this condition. Changes in markers of oxidative stress and inflammation were measured. The children were evaluated to determine clinical effects and safety. |
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