Pedigree analysis and epidemiological features of idiopathic congenital talipes equinovarus in the United Kingdom: a case-control study期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Pedigree analysis and epidemiological features of idiopathic congenital talipes equinovarus in the United Kingdom: a case-control study

Authors:	AH Cardy S Barker D Chesney L Sharp N Maffulli Z Miedzybrodzka

Affiliation:	(1) Department of Public Health, University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen, AB25 2ZD, UK;(2) Department of Orthopaedic Surgery, Aberdeen University School of Medicine, Polwarth Building, Foresterhill, Aberdeen, AB25 2ZD, UK;(3) Freeman Hospital, Freeman Road, Newcastle upon Tyne, NE7 7DN, UK;(4) National Cancer Registry of Ireland, Elm Court, Boreenmanna Road, Cork, Ireland;(5) Department of Trauma and Orthopaedic Surgery, Keele University School of Medicine, Thornburrow Drive, Stoke on Trent, ST4 7QB, UK;(6) Department of Medicine and Therapeutics, University of Aberdeen, Polwarth Building, Foresterhill, Aberdeen, AB25 2ZD, UK

Abstract:	Background Congenital talipes equinovarus (CTEV) is a common developmental disorder of the foot, affecting between 1 and 4.5 per 1000 live births. The aetiology is not well elucidated. While both genetic and environmental factors are implicated, no specific genes have been identified and little is known about environmental risk factors.

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