Novel phytoandrogens and lipidic augmenters from Eucommia ulmoides |
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| Authors: | Victor YC Ong Benny KH Tan |
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| Affiliation: | (1) Department of Pharmacology, Yong Loo Lin School of Medicine, National University of Singapore, 10 Kent Ridge Crescent, 119260, Singapore;(2) Faculty of Medicine, Nursing and Health Sciences, Monash University, Wellington Road, 3800 Victoria, Australia |
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| Abstract: | ![]()
Background Plants containing compounds such as the isoflavonoids, with female hormone-like effects that bind to human estrogen receptors, are known. But none has been previously shown to have corresponding male hormone-like effects that interact with the human androgen receptor. Here, we report that the tree bark (cortex) of the Gutta-Percha tree Eucommia ulmoides possesses bimodal phytoandrogenic and hormone potentiating effects by lipidic components. |
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