Differentiation-inducing quinolines as experimental breast cancer agents in the MCF-7 human breast cancer cell model |
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| Authors: | Martirosyan Anna R Rahim-Bata Rayhana Freeman Andrew B Clarke Charles D Howard Rachael L Strobl Jeannine S |
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| Affiliation: | Department of Biochemistry & Molecular Pharmacology, West Virginia University, Morgantown, WV 26506, USA. |
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| Abstract: | |
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| Keywords: | HDAC, histone deacetylase MTS, 3-(4,5-dimethylthiazol-2-yl)-5-(3-carboxylmethoxyphenyl)-2-(4-sulfophenyl)-2H-tetrazolium PAMPA, parallel artificial membrane permeation assay Rb, retinoblastoma protein Amodiaquin, 4-[(7-chloro-4-quinolinyl)amino]-2-[diethylamino)methyl]phenol Chloroquine, N4-(7-chloro-4-quinolinyl)-N1,N1-diethyl-1,4-pentanediamine Halofantrine, 1,3-dichloro-α-[2-(dibutylamino)ethyl]-6-(trifluoromethyl)-9-phenanthrenemethanol Hydroxychloroquine , 2-[[4-[(7-chloro-4-quinolinyl)amino]pentyl]ethylamino]ethanol Mefloquine, piperidinyl-2,8-bis(trifluoromethyl)-4-quinolinemethanol) Quinidine , (9S)-6′-methoxycinchonan-9-ol Quinine, (8-α,9R)-6′-methoxycinchonan-9-ol Primaquine, N4-(6-methoxy-8-quinolinyl)-1,4-pentanediamine NSC10010, N,N-bis(2-methyl-6-methoxy-4-quinaldyl)-1,9-diamine-nonane dihydrochloride hydrate NSC3852, 5-nitroso-8-quinolinol NSC69603, 4-(2-(2,5-dimethoxyphenyl)vinyl)quinoline NSC86371, 2-[2-(8-hydroxy-5-methyl-7-quinolyl)vinyl]-1,6-dimethyl iodide NSC305819, 1-(2,8-bis(trifluoromethyl)-4-quinolinyl)-3-(tertbutylamino)-1-propanol |
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